CBD Health

First off, what is CBC? CBC is a minor cannabinoid called cannabichromene (CBC). Being a minor cannabinoid is one of the reasons we don’t hear much about CBC. It is not found in very high percentages compared to other major cannabinoids such as cannabidiol (CBD). This can make the extraction costly, which is another reason you don’t hear much about it, but you should because CBC has many benefits and uses as a medicine.

The anti-inflammatory effects of CBC are of great benefit to people with pain and other ailments caused by inflammation, as well as people with autoimmune diseases that cause increased inflammation and several other inflammatory conditions. One study directly examined the pharmacological potential of CBC and found that CBC was effective “dose-dependent” anti-inflammatory effect“. [1]

Another study, published in Neurochemistry International, discovered that CBC was an excellent cannabinoid for brain health. It was even compared to CBD and CBG, and the results showed that CBC has beneficial effects on neural stem progenitor cells. These cells are essential for healthy brain function, and CBC increased their viability, making CBC a potential candidate for treating disorders related to brain cells and brain health. [2]

If that’s not enough to talk about CBC, what if you found out that CBC was shown to be effective in treating cancer? So effective in fact research Studying the effectiveness of several cannabinoids on anti-tumor activity in breast cancer may have found that CBD is the most effective at inhibiting tumor growth, but CBC came right behind it. This means that CBC can help stop tumors from growing. Maybe not as much as CBD, but enough to take second place. [3]

Despite these and many other medicinal benefits of CBC, there is a good chance it will take a back seat to better-known cannabinoids like CBD for the time being. As the science of cannabinoid medicine advances, other cannabinoids like CBC will gain ground to be better recognized and discussed as more of their true potential is discovered.

References:

1- DeLong, G., et al., Pharmacological Evaluation of the Natural Ingredient of Cannabis sativa, Cannabichromene and its modulation by Δ⁹-Tetrahydrocannabinol. Drug and alcohol addiction. 2010. 112, (1-2) 126-133. https://www.sciencedirect.com/science/article/abs/pii/S0376871610002073

2- Shinjyo, N., et al., The Effect of Cannabichromes on Adult Neural Stem / Progenitor Cells. Neurochemistry International. 2013. 63. (5) 432-437. https://www.sciencedirect.com/science/article/abs/pii/S0197018613002106

3- Ligresti, A. et al., Antitumor Activity of Plant Cannabinoids, Emphasizing the Effect of Cannabidiol on Human Breast Cancer. Journal of Pharmacology and Experimental Therapeutics. 318 (3) 1375-1387. https://jpet.aspetjournals.org/content/318/3/1375.long

Testing has become a fundamental part of the cannabis industry. Laboratories have sprung up across the country to provide testing services to the hundreds of companies that now exist in this fast growing industry. One of the most important things these labs test for is the presence and concentration of cannabinoids, both large and small, using a variety of high-tech tools and equipment.

Several Dozens of cannabinoids found in cannabis. However, not all of them are that valuable to the cannabis industry, at least not yet. Currently, the most valuable cannabinoids are tetrahydrocannabinol (THC) and cannabidiol (CBD), which are known as the most important cannabinoids.

As the industry matures and research continues, other cannabinoids are known as the smaller cannabinoids, can prove to be just as valuable as THC and CBD. These other cannabinoids of interest currently include tetrahydrocannabinolic acid (THCA), tetrahydrocannabivarin (THCV), cannabidiolic acid (CBDA), cannabidivarin (CBDV), cannabigerol (CBG), and cannabichromene (CBC). When speaking of these minor cannabinoids, it is important to understand that the term “inferior” does not refer to the effect these cannabinoids have on their users. Rather, the term “minor” refers to their concentrations in cannabis plants – the main cannabinoids are more abundant than the smaller ones, hence the terminology.

When labs test for cannabinoids, they use two principles Test methods: Ultra High-Performance Liquid Chromatography (HPLC) and Gas Chromatography (GC). Both tests tell you what cannabinoids are in a sample and also show you how concentrated they are in the sample.

However, both tests are not the same. In fact, HPLC is often the preferred test when handling cannabis and cannabinoids because it is a test method that can be done at room temperature. While GC tests require a heat catalyst to trigger a reaction in the sample to detect cannabinoids present. This heat catalyst prevents GC tests from detecting the cannabinoids THCA and CBDA, which turn into THC and CBD when heated. In other words, HPLC is a more comprehensive test for cannabinoids.

Image source: https://www.pexels.com/photo/set-of-glass-tube-in-laboratory-4021793/

Projections of Statista estimate that cannabidiol (CBD) sales will grow to $ 1.8 billion by 2022, up from just under $ 0.5 billion in 2018. If you’re an investor looking to weather this wave, here’s a breakdown of the top CBD products made from the Shelves have flown.

CBD gummies

CBD gummies remain an all-time favorite for busy mothers who want to incorporate delicious CBD treats into their everyday lives. Gummies are available in sizeable doses such as 5 mg, 10 mg, and 20 mg, which make dosing easier. They don’t require any special skills or tools to consume. All you have to do is toss a gummy bear or two in your mouth and wash it down with your favorite beverage. Compared to capsules, gummy bears come in brightly colored and delicious variants and are therefore more attractive. If you need to offer kids CBD, gummy bears are the way to go. It’s no surprise that they are among the top-selling CBD products.

Some of the best-selling CBD gums on the market include the Lord Jones gummy candies, which have lemon and strawberry flavors and contain 20 mg of broad spectrum CBD.

CBD vapes

Vaping is a pretty nifty way of consuming CBD. Manufacturers have worked hard to grab the attention of the younger population by making cheeky vaporizers in a variety of flavors. Like e-cigarettes, vaporizers deliver CBD to the lungs quickly; Blood peaks occur after about 10 minutes and the effects can last for up to 3 hours. This makes vaping an ideal way to relieve anxiety in high pressure situations.

The safety of CBD vapes was approved in 2019 following the Steam crisis. This, of course, affected sales of CBD vapes. However, there was a rebound in sales following analytical reports that the steam crisis was due to contamination with vitamin A acetate. Manufacturers who can determine the safety of the CBD vapes can continue to enjoy dominance in the market. Some of the most popular CBD vapes on the market are the artisanal CBD vape pens from Secret Nature and the exquisite vape pens from Funky Farms.

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This is a highly diversified product category that has taken the skin care market by storm. Skin care manufacturers are rushing to add CBD to their product repertoire for its purported skin benefits. The best-selling CBD skin care products containing CBD include bath bombs, lotions, creams, ointments, and patches, among others. Topicals are applied directly to the skin and are easily absorbed by the numerous endocannabinoid receptors located there. They have wide appeal because they are effective in fighting skin diseases.

What’s in the future?

We expect product inventions and diversification in the CBD sector. The fierce competition in the market will force manufacturers to be more resourceful when it comes to product development. It will be interesting to see how this space evolves in 2021 and 2022 as we get closer to the $ 1.8 billion mark.

Image source

https://pixabay.com/id/vectors/best-seller-penjual-cap-merah-158885/

While you can include cannabidiol (CBD) in your daily intake at any time by placing a drop under your tongue or vaping it, you can also take advantage of its healing properties while enjoying a meal or a sweet treat.

CBD can easily be added to some of your favorite recipes and enjoyed as a homemade edible, but there are a few basic rules that you must follow to get the most of cooking with CBD oil.

Consider the serving size

Make sure you factor in the serving size of the dish you are preparing or the batch of baked goods you bake so that the CBD concentration is sufficient to achieve the desired dosage. For example, if you want 20 mg of CBD in every cookie you make from a batch of 24, you need about 480 mg of CBD added to the entire batter. Adjust this based on the serving size and the exact dosage you are looking for per serving.

Do not cook over high heat

Overheating the CBD could destroy the active ingredients in the cannabinoid and make it less effective. When heating the oil on the stove do not keep the burner higher than medium. And when you bake, try not to set your oven above 350 ° F. Otherwise, the CBD could evaporate.

If possible, add the CBD oil to your dish after cooking. Otherwise, be careful how hot you turn up the heat on your stove or oven when cooking or baking directly with CBD.

Keep the taste in mind

Many CBD tinctures tend to have a bitter taste, so you might want to add some flavor to make it tastier. However, many other CBD products have different flavors that are reminiscent of berries, honey, citrus fruits, mint, etc.

When choosing a CBD oil, keep in mind the dish you plan to prepare as the flavors may not mix as well as you would like. It may take a little experimentation before you get it just right and create perfect flavor combinations.

Use a fat base

CBD works quite well when the recipe includes a healthy fat, such as coconut oil, olive oil, ghee, or butter. Because of this, CBD oil is perfect for baking and cooking. You may even want to mix your CBD with the fat you use in your recipe before mixing it with the rest of the ingredients.

Image source: Galina Afanaseva from Pixabay

When it comes to the therapeutic potential of cannabidiol (CBD), researchers have only scratched the surface.

This phytocannabinoid, which was first isolated in 1940, has far-reaching effects due to its interactions with the receptors of the dynamic endocannabinoid system (ECS). Other Mechanisms and ways got involved too.

Diabetes, which affects about affects 32 million Americans, is a chronic disease that is associated with a disorder in the production or sensitivity of insulin. To date, no known medical cure is known for diabetes, although naturopaths often swear by nutrition-assisted diabetes reversal.

Since the endocannabinoid system is involved in maintaining a state of homeostasis in the body, it would be interesting to know what role it plays in controlling diabetes and how much of it can be influenced by CBD.

To determine this, it is important to look at the research results.

About 95% of diabetics have type 2 diabetes, which occurs when cells in the body become insensitive to insulin, also known as insulin resistance. This means that there is a large amount of sugar floating around. If this continues for a long period of time, it can cause significant inflammation that begins to damage the blood vessels.

The anti-inflammatory effects of CBD have been studied for decades. A study from 2007 entitled “Cannabidiol attenuates inflammatory reactions of endothelial cells and barrier disorders induced by high glucose” is one of interest for diabetes control. [1]

This study showed that CBD exerted potent anti-inflammatory and antioxidant effects in non-obese diabetic mice. CBD has been shown to have beneficial effects on a number of markers of inflammation. This shows one way that CBD can mitigate some of the damage caused by chronic inflammation in diabetics.

This study also showed that the non-obese diabetic mice treated with CBD had a lower risk of developing diabetes. This forms a good basis to examine in randomized studies whether there is a similar effect in humans.

Patients with advanced diabetes may experience neuropathic pain commonly known as diabetic nephropathy.

Another study published in the Journal of Experimental Medicine, demonstrated the effectiveness of CBD in suppressing neuropathic pain in a rodent model. [2]

On the other hand a Study 2016 published in Diabetic Care showed low effectiveness of CBD on HDL cholesterol levels and other markers, including insulin sensitivity. [3]

In conclusion, there is enough preliminary evidence that CBD can be effective in relieving diabetes inflammation and pain, as well as preventing diabetes in non-obese individuals. On the other hand, there is insufficient evidence to support the effects of CBD on HDL cholesterol or blood sugar levels.

Image source

https://pixabay.com/photos/diabetes-blood-sugar-diabetic-528678/

References

1. Mohanraj Rajesh et al. (2007). Cannabidiol dampens the inflammatory reaction of the endothelial cells induced by high glucose and the barrier disruption. American Journal of Physiology-Cardiovascular Physiology. 293: 1, H610-H619
2. Wei Xiong et al. (2012). Cannabinoids suppress inflammatory and neuropathic pain by targeting α3-glycine receptors. Journal of Experimental Medicine. 209 (6): 1121-1134.
3. Jadoon, KA, Ratcliffe, SH, Barrett, DA, Thomas, EL, Stott, C., Bell, JD, O’Sullivan, SE, & Tan, GD (2016). Efficacy and safety of cannabidiol and tetrahydrocannabivarin on glycemic and lipid parameters in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled, parallel-group pilot study. Diabetes treatment, 39(10), 1777-1786.

One recently Article in Forbes described the Delta-8 (D8) frenzy as “a story of American ingenuity”. Delta 8 product sales have exploded in the recent past. This was good for both hemp farmers who had to dispose of their excess biomass and end users who could enjoy the feeling of getting “legally high” as it was described. On the other hand, it has led state regulators in some states to ban the sale of this cannabis-sativa-derived compound. But while we’re still enjoying the D8 frenzy, how will this affect CBD sales? are CBD and D8 Complementary or competing products?

The question begs another question, why are consumers turning to D8 and, for the same reason, why are they turning to CBD?

CBD sales have grown steadily over the years. It is estimated that the global CBD market will reach $ 2,740 million this year and will grow at a CAGR of around 51% over the 10 year period to 2030. This growth is accelerated by the entry of dominant players as well as smaller ambitious start-ups into the market. The therapeutic potential of CBD is a driver for clinical trials that also contribute to regional market growth.

However, CBD is not intoxicating and therefore has no meaning as a recreational substance.

Delta-8, like other cannabinoids, has therapeutic potential that deserves further research. The D8 frenzy, however, has more to do with the therapeutic potential of this Delta-9-THC analog.

The market in general is excited about the psychotropic properties of D8. Some consumers have described the D8 high as invigorating without having extreme effects like paranoia. The novelty and the legal gray area are another exciting feature that makes D8 attractive to younger age groups. The producers also get very creative in the way they market D8 products which, unlike THC products, are easily accessible from gas stations and shops.

Placed side by side, the D8 frenzy is highly unlikely to harm CBD sales in any way. Consumers turn to the two products for different reasons, and the type of clientele is also very different. While the CBD group is the most medicinally, the D8 group is mostly made up of recreational users. As a result, it can be assumed that sales of both products will continue positively for the foreseeable future, as the two complement each other rather than competing products.

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There is no age limit for the daily use of cannabidiol (CBD). Seniors can benefit from the cannabinoid just as much as anyone else, and the diseases that are more common in this population group make CBD a potentially useful addition to improving the quality of life of an aging person.

Here are some ways seniors can benefit from CBD.

Pain

As the body ages, there is a tendency for the aches and pains to increase, so many seniors may have a range of pain relievers in their medicine cabinet. But in addition to – or in place of – pharmaceutical medications, seniors may find CBD helpful in relieving their pain.

Studies show that the interaction of CBD with the endocannabinoids of the endocannabinoid system can help relieve pain, regardless of whether the cannabinoid is taken orally for a systemic effect or applied topically to treat certain ailments, be it arthritis, fibromyalgia, Circulatory problems, bowel disease, or any other disease that becomes more common with age. [1]

glaucoma

glaucoma includes a number of eye diseases that can damage the optic nerve and affect good vision. This damage is typically caused by increased intraocular pressure and is a major cause of blindness in people over the age of 60. In fact, the prevalence of the most common form of glaucoma increases with age.

There is growing evidence that cannabinoids like CBD can help ward off the harmful effects of glaucoma by lowering intraocular pressure. [2] This, in turn, can help slow down the harmful effects of glaucoma.

Alzheimer

Researchers are now investigating how CBD can play a role in treating or preventing Alzheimer’s disease. The results of the studies conducted so far show great potential for the cannabinoid and suggest that CBD may suppress the main factors linked to Alzheimer’s, including the elimination of a specific toxic protein associated with the disease. [3]

Additionally, scientists suggest that using CBD in conjunction with tetrahydrocannabinol (THC) could prove even more useful for this purpose.

Bone health

The elderly are more prone to bone loss as they age, which can lead to bone conditions like osteoporosis, which involve weakening bones to the point where they are easier to break. Interestingly, CBD can help slow down bone breakdown that can lead to diseases like these.

Studies have shown that cannabinoid receptors are expressed in bone and are involved in the regulation of bone homeostasis in both rats and humans. [4] The use of CBD as a treatment has been linked to improved fracture healing in rodents. However, further validation through clinical studies is justified.

Image source: Steve Buissanne from Pixabay

References:

1. Russian, EB, “Cannabinoids in the treatment of hard-to-treat pain“Ther Clin Risk Manag., Feb 2008, 4 (1): 245-259.

2. Tomida, i, et al. “Cannabinoids and glaucoma“, Br. J. Ophthalmol., May 2004, 88 (5): 708-713.

3. Kim, SH “A look back at studies on marijuana in Alzheimer’s disease – with a focus on CBD, THC“, J Pharmacopuncture, December 2019, 22 (4): 225-230.

4. Raphael-Mizrahi, B. & Gabet, Y., “The effects of cannabinoids on bone formation and healing“, Curr Osteoporos Rep., October 2020, 18 (5): 433-438.