CBD Health

Cannabidiol can effectively treat chronic pain without causing devastating side effects: Here’s how

Dallas, TX, May 12, 2021 – The United States is facing a major drug crisis, largely due to chronic pain, overprescription, and opioid addiction. The Centers for Disease Control estimates that just over twenty percent of adults in the United States (nearly half of whom are considered severely affected). Chronic pain has been associated with reduced mobility, anxiety, depression, decreased quality of life, and opioid addiction.

Even in the face of this grim news, there is hope. David Schroeder’s new book, 7 Ways to Treat Pain with CBD, has been hailed as the “CBD Pain Management Bible” and has been well received as a comprehensive guide to using cannabidiol for pain management. 7 Ways to Use CBD to Manage Pain, weaves narrative with documented sources and dispels myths while readers are educated.

David wrote the book to help others after facing a variety of information and misinformation on the subject. Carefully researched, 7 Ways to Use CBD to Treat Your Pain is an easy-to-understand guide to understanding the basics and uses of CBD. This book covers topics such as defining CBD and ensuring its quality and accuracy, from risks (both side effects and legality) to dosage and formulation guides

After playing in the NFL for over a decade, you’ll understand when I say this book should be in every locker for the guys to know about the CBD alternative to opioids. David’s book takes you from beginner to expert in a clear, precise and understandable way. For someone who wants to know everything about CBD or has questions, this is the book for them

– Marvin Washington, 1998 NFL Super Bowl Champion, Board Member – Isodiol International Inc.

As more people use CBD, it becomes more and more urgent that there be a comprehensive guide that will enable people to use CBD effectively and safely without falling victim to charlatans

There are 7 ways to treat pain with CBD on David’s website: The CBD Writer | Amazon | Barnes & Noble.com | Walmart.com | Kobo.com

David Schroeder is one of the country’s leading proponents for the use of cannabidiol (CBD) for therapeutic pain management. Mr. Schroeder is a self-taught expert on CBD out of personal need. After battling chronic pain for many years, David came across a CBD pain stick – which paved the way for his haunted quest in the CBD arena

To what extent can our expectations modulate positive CBD effects on anxiety and stress? Is there a connection between our beliefs and the actual pharmacological effects of this cannabis phytochemical substance?

The answer to these questions is based on the most recent scientific research by Spinella et al. (2021) [1], in which for the first time CBD-linked placebo reactions to stressful mental states are systematically analyzed. A randomized crossover study in healthy adults was conducted to test the weather. The CBD expectation alone could have a positive effect on acute stress and anxiety. Heart rate (HR) and heart rate variability (HRV) are the physiological parameters that need to be measured to assess the stress response. The root mean square of consecutive differences (RMSSD) reflects the beat-to-beat variance in the HR [2] and a lower value thereof indicates a greater voltage response.

During the first orientation meeting, cannabis uses the frequency and a priori Each participant’s CBD expectations and beliefs were collected using individual questions. Two experimental sessions followed: Participants were subjected to the Maastricht Acute Stress Tests (MAAST) to elicit subjective and physiological responses related to stress and anxiety. MAAST includes 5 minutes of explanation of the procedures and 10 minutes of cold pressure tests [3] : Participants took turns putting their hand in ice-cold water and counting backwards in increments of 17 or 13, starting with a random four-digit number, while being pressured by negative social rating feedback. [1] CBD hemp-free oil was administered during both experimental sessions, but participants were misinformed about the presence of CBD in the oil in one of the two experiments. Spinella et al. [1] found that strong basic expectations about CBD-reducing anxiety are linked to decreased subjective anxiety. For those without being strong a priori Beliefs about CBD effects and expectant mood changes were not identified. This study is additional confirmation of the expectation theory proposed by Kirsch in 1985 that the expectation that a certain reaction will occur increases the likelihood that that reaction will actually occur. [4]

A better understanding of the correlation between active response and non-pharmacological CBD influence on anxiety could help improve the design of clinical research experiments, thus defining specific therapeutic treatments.

References:

[1] Spinella TC et al. Evaluating the effects of cannabidiol (CBD) expectation on acute stress and anxiety in healthy adults: a randomized crossover study. Psychopharmacology. (2021) https://doi.org/10.1007/s00213-021-05823-w [Journal Impact Factor = 3.424]

[2] Minarini, G. Root Mean Square of the successive differences as markers of the parasympathetic nervous system and difference in the result after ANS stimulation. Monitoring the autonomic nervous system – variability in heart rate. (2020) doi: 10.5772 / intechopen.89827

[3] Smeets T. et al. Introducing the Maastricht Acute Stress Test (MAST): A rapid and non-invasive approach to eliciting robust autonomic and glucocorticoid stress responses. Psychoneuroendocrinology, 37 (12), 1998-2008. (2012) doi: 10.1016 / j.psyneuen.2012.04.012
[Times cited = 186 ] [Journal Impact Factor = 4.732]

[4] Kirsch, I. (1985). Answer expectation as a determinant of experience and behavior. American Psychologist, 40 (11), 1189-1202. https://doi.org/10.1037/0003-066X.40.11.1189 [Times cited = 1200] [Journal Impact Factor = 6.54]

Picture: https://bionewscentral.com/new-study-gives-the-most-detailed-look-yet-at-the-neuroscience-of-placebo-effects/

CBDfx is launching new edible CBD products to meet the growing demand for on-the-go nutrition.

Los Angeles, CA (May 13, 2021): Leading company for CBD products, CBDfx, launches several edible CBD products, including Protein Cookies, Chill & Focus Shots, and 8-Count Rubber Pouches, aimed at consumers in the convenience store on the go, with the perks they want most: Quality , natural ingredients and an increased sense of calm for their busy lifestyle.

The CBD beverage and food markets are growing significantly as consumers become more familiar with CBD in the food and beverage form. The CBD beverage market alone is expected to reach $ 1.5 billion by 2025, according to the Brightfield Group. Consumers drink CBD beverages with specific wellness effects in mind and look for functional beverages with clean ingredients, low sugar levels, and reduced calories.

“CBD edible products like gums, beverages and baked goods are growing in popularity and attracting new users with CBD users as they are a convenient and easily measurable way to add wellness-enhancing CBD to your diet,” said Jameson Rodgers, co-founder. “Our new natural CBD foods are optimized for a variety of health benefits, from antioxidants and pure protein to revitalizing multivitamins and natural amino acids like L-theanine for relaxation. All packaged as delicious and inexpensive portable treats for on the go. “

The new CBDfx products have been designed with bold packaging and bright colors that jump off the shelf.

• CBD Vegan Protein Cookies:: Natural biscuits packaged with 20mg broad spectrum CBD and 13g pure plant-based protein. CBD cookies come in three flavors: chocolate chips, peanut butter, and oatmeal raisin. They offer one of the highest absorption rates and a longer lasting CBD experience as CBD is slowly released as food is digested. It retails for $ 4.99 at retail stores across the country or $ 14.97 for a mix-and-max three-pack on CBDfx.com.

• CBD chill shots:: CBDfx Chill Shots are ready to drink (but best chilled!) And combine 20 mg broad spectrum CBD, 200 mg L-theanine for relaxation, and a range of vitamins and minerals known for their calming effects – including vitamin B6, magnesium and Zinc. This “relax” formula is available in lemonade and berry flavors and retails for $ 4.99 or $ 14.97 for a mix-and-max three-pack on CBDfx.com in retail stores across the country.

• CBD focus shots:: A ready-to-drink beverage containing 20 mg of broad-spectrum CBD, 150 mg of energizing L-arginine, 75 mg of caffeine, and a variety of revitalizing vitamins and minerals, including vitamins C, B3, B6, B12, and D. Available in two flavors – pomegranate and tropical – this “alarm” formula costs $ 4.99 and is designed to increase focus and generate new energy. Available in retail stores across the country or on CBDfx.com for $ 14.97 for a Mix-and-Max 3-pack.

• CBD rubber bags with 8 counters: The award-winning vegan CBD gummies from CBDfx in a practical and travel-friendly bag with 8 counters. With 50 mg CBD with a broad spectrum per serving, these naturally sweetened foods are available in six variants with different therapeutic effects, from supporting sleep to multivitamins: Original Mixed Berries, Turmeric & Spirulina, Melatonin, Apple Cider Vinegar and Multivitamin for men and women . It retails for $ 9.99 per bag of 8.

About CBDfx: CBDfx is a Southern California based company founded to provide high quality, organic cannabidiol (CBD) care products to customers in a variety of formats. from tinctures to topicals and gums to capsules. Founded in 2014 with the aim of bringing quality to the forefront of the CBD industry, CBDfx offers some of the best, purest and most effective CBD products in the world. CBDfx products are sold in more than 32,000 outlets in 21 countries and online at www.CBDfx.com.

Based on the best-selling cancer book from Amazon with the title “My Way”, in which the
Journey of Curing an Aggressive Cancer with Fully Extracted Cannabis Oil, Author Dee
Mani-Mitchell decided to open a branch of CBD oils and wellness products with a
Difference.

The success of her book led Dee to start My Way CBD to specialize in natural CBD
Healing solutions that add value to the world of natural healing by revolutionizing posture
towards hemp products and the wellness cannabinoids bring human lives.

Dee is a columnist for two medical marijuana publications and writes with the goal of one
better understanding of our health, our world and our place in it. A mission that has occupied them
in many different roles: writer, motivator, supporter, inspirer, advocate and awareness builder.
A successful business woman who has personally relied on cannabis for many years
She deals with her own health problems and is constantly breaking down barriers with her beliefs
This healing should be built into our more natural life.

Dee is on a mission – to improve the quality of life through natural and effective healing
Solutions. The exciting part is that Dee has developed a completely unique line of CBD
Infusions. As part of her daily life, she leads a cancer support group in which she works
Recommends patients add essential oils to their healing protocol if they help with treatment
Apoptosis (cancer cell death). Pure, organic, food-safe (ingestible) essential oils
often come at a high price. So Dee decided to include some very powerful essentials
Oils with their range of broad spectrum CBD to be more affordable for people who want it
Take both CBD and high quality essential oils.

My Way CBD infusions of frankincense, myrrh, ashwagandha, ginger and oregano
Oil. All essential oils are organic and safe for internal use, containing 10% of the essential oil
every 30ml bottle of goodness. Those IVs fly out of the store and there is one
Plan to add various powerful combinations to the full spectrum.
My Way guarantees an entire product range with a “complete transparency” and a strict “no
evil policy “, which is always free from harmful chemicals, pesticides, solvent residues,
Toxins, chlorophyll, fats and lipids, preservatives, sulfates, mineral oils, parabens, animals
Tests, artificial colors and perfumes. All products are also vegan, GMO-free and kosher.
All products are formulated with the most refined laboratory tested CBD oils that are certified in both UK countries
and US laboratories.

To check the area, go to www.mywaycbd.com
For information on cancer support, see www.deemani.com

Cannabidiol has been involved in the treatment of various medical conditions. Although the affinity is missing It has shown potential as a regulator of the immune system for both the CB1 and CB2 receptors through various mechanisms.

When it comes to Sjogren’s, there are no studies that directly link the condition to CBD. However, this doesn’t rule out potential benefits of CBD in alleviating some of the lingering symptoms of the condition.

Sjogren’s is an autoimmune system disorder characterized by persistent dryness of the mouth and eyes. This happens when the mucous membranes in your eyes and mouth dry out.

Initially, these are symptoms that over-the-counter medications can easily be written off or alleviated. However, over time, symptoms can become more severe and persistent. New symptoms can include vaginal dryness, rashes, joint inflammation, insomnia, and excessive fatigue.

As with most other autoimmune diseases, there is no known cure for Sjogrens syndrome. The etiology is also unclear, but middle-aged women are at greater risk of developing it.

As a result, treatment usually focuses on symptom control.

Traditional treatment for Sjogren’s includes the use of over-the-counter pain relievers, anti-inflammatories, eye drops, antifungals for mouth infections, hydroxychloroquine, and methotrexate to suppress the exaggerated immune response.

When it comes to symptom control, CBD could offer several benefits, particularly as an immunosuppressant.

Patients with Sjogren’s who have trouble falling asleep can use CBD to relax and promote restful sleep. With restful sleep, Sjogren sufferers are likely to be less tired and this will increase their productivity.

In one study, CBD was shown to suppress both innate and adaptive immune responses. [1] CBD reduces levels of cytokines, which are molecules that trigger the inflammatory process. This is known as the “endocannabinoidoma” phenomenon and describes the interaction between the immune system and the endocannabinoid system.

While the mechanisms by which CBD affects the immune system are diverse, the end result is the same. Suppression of the immune system likely suppresses autoimmune diseases like Sjogren’s.

In another study, patients with SS were given methotrexate, which improved symptoms such as dry eyes, dry mouth, dry cough, and purpura. [2]

As mentioned earlier, there is a lack of scientific evidence linking CBD and Sjogren’s. However, it would be interesting to know if CBD can be compared to methotrexate or other drugs that have been shown to be effective in treating the condition.

Image source

https://commons.wikimedia.org/wiki/File:Sjogrens_Syndrome.jpg

References

1. James M. Nichols and Barbara LF Kaplan. (2020). Cannabis and cannabinoid research.

Volume 5, Issue 1. 12-31.

2. Skopouli, FN, Jagiello, P., Tsifetaki, N. & Moutsopoulos, HM (1996). Methotrexate in primary Sjogren’s syndrome. Clinical and Experimental Rheumatology, 14th(5), 555-558.

There are several ways to consume cannabidiol (CDB), including through tinctures, oils, topicals, foods, and through vaporizing.

An interesting way of consuming it is sublingual wafers, which are placed under the tongue and dissolved so that the active CDB can be absorbed directly into the bloodstream without going through the digestive process.

You may have seen sublingual wafers in other forms, including those used to deliver vitamins. The purpose of sublingual wafers is to ensure rapid dissolution, accelerate the action of the active ingredient on the body and increase its bioavailability. In these cases, sublingual CBD wafers can be an attractive option for those who want to ensure a faster effect of CBD, among other things to relieve pain, reduce inflammation, or soothe anxiety.

A study recently conducted and published in the British Journal of Clinical Pharmacology examined the safety and tolerability of CBD wafers and oils compared to cannabinoid-based oromucosal sprays. [1]

Twelve study participants received 4 different single doses of CBD as a sublingual wafer, oil or oromucosal spray and were evaluated on the basis of the tolerability of the doses. The pharmacokinetics of CBD uptake were also closely followed.

The volunteers received a sublingual CBD wafer twice daily for 5 days in a multiple dose study.

The researchers found that the CBD was well tolerated among participants when the cannabinoid was given in either wafer or oil format, although some side effects were noted, including sedation and altered mood. The bioavailability of the CBD was comparable for wafer and oil. CBD concentrations were maximized 4 hours after consumption.

No statistically significant difference was found between the observed CBD exposure after administration of the wafer or the oil solution compared to the oromucosal spray.

Image source: Alissa De Leva from Pixabay

References:

1. Hosseini, A, et al.A Phase I study of the safety, tolerability, and pharmacokinetics of cannabidiol administered as a single-dose oil solution and as a single and multiple dose of a sublingual wafer in healthy volunteers“, British Journal of Clinical Pharmacology, October 2020.

The internet is full of claims about the health benefits of cannabis, but are they true? This was the question asked by a group of researchers who decided to search the internet for health claims related to cannabis and compare them to available scientific research to determine their validity. your study was recently published in the Journal of General Internal Medicine and they found most of the claims to be false, meaning they do not have enough scientific evidence to credibly support the claims. [1]

We came to that conclusion by searching Google and searching the top ten websites for the terms “marijuana benefits,” “weed benefits,” and “marijuana health.” To include articles that were mentioned on social media, the group used buzzsumo and searched for the terms “marijuana benefits OR cannabis benefits OR weed benefits” and “marijuana health.” Once the top websites and social media articles were collected, they were reviewed and each of the health claims was categorized, rated, and rated using published systematic reviews and randomized controlled trials available on Medline.

In the end, a total of 467 individual health claims were identified and divided into 81 categories. The most common health benefit claim for cannabis emerged Pain relief. However, claims related to the general pain category were ultimately classified as “not true” along with cancer, anxiety, PTSD, neuroprotection, and Alzheimer’s disease. On the other hand, the treatment of chemotherapy-induced nausea and spasticity caused by multiple sclerosis has been found to be “true” and it is claimed that cannabis is effective in treating seizures and seizures sleep were rated as “partially true”.

Overall, only 4.9% of all entitlement categories were rated “true”, which suggests that we cannot always trust what the internet has to say, but that is not new information. The search terms used for this study, particularly on Google, excluded the word cannabis and included the terms “marijuana” and “weed”, both of which are not used by cannabis industry professionals. This search term variable could easily have skewed the search results because they are heavily made up of unreliable resources to begin with. As always, when it comes to information on the Internet, choose your sources wisely.

References:

Lau, N. et al. Internet claims on the health benefits of cannabis use. Journal of General Internal Medicine. 2021. https://doi.org/10.1007/s11606-020-06421-w